Extruder Spheronizer
The extrusion spheronizer is composed of an extruder and a spheronizer. It features a unique low-shear basket extruder design with low temperature rise, including feeding paddles, extrusion paddles, and screens. Different specifications of screens can be selected based on the material characteristics and microsphere size. The main component of the spheronizer is a high-speed rotating friction disc with compressed air blow cleaning at the bottom of the disc, resulting in high spheronization efficiency and the production of microspheres with high sphericity and narrow particle size distribution.
- Unique low-shear basket extrusion method, short extrusion path, flexible extrusion, low temperature rise, particularly suitable for handling thermosensitive materials.
- Precision-machined screens ensure uniform microsphere particle size and ultra-high surface quality. Multiple specifications of extrusion screens are available for selection.
- The unique gear design prevents damage to the microspheres at the edge of the gear, resulting in high yield. Radial and orthogonal gear options are available.
- The integrated design of the extruder and spheronizer enables automated continuous production.
- The equipment has a high degree of automation, fully automatic batch production mode, production formula management, multi-level user access management, audit trail, and electronic records. Production reports can be stored and printed, fully meeting the requirements of 21CFR part 11.
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With advanced low-shear extrusion and excellent performance, it is suitable for the production of microspheres in the pharmaceutical industry, especially for high drug load and thermosensitive materials.
