Isolation technology first originated from the glove box technology used in the Second World War, and with the development of the pharmaceutical industry, the application of isolation technology has become increasingly widespread. At present, the main isolation systems commonly used in the international are sterile isolator (Isolator) and restricted access barrier system (RABS). Since 2009, we have been systematically researching and developing all kinds of isolation devices, and in 2011, we introduced the advanced technology of Japan Airex and cooperated to set up Shanghai Tofflon Airex Technology Co. In May 2013, we passed the certification of IOS9001 quality system, and participated in writing and revising the barrier system of Appendix I of 2022 edition of GMP, and drafted the “Aseptic Isolator”, “Vaporized Hydrogen Peroxide Sterilization Generator”, ‘Vaporized Hydrogen Peroxide Transfer Chamber’ and other related industry standards.