Cell Therapy Solution

In 2010, Emily, a 5-year-old patient with acute lymphoblastic leukemia, received CAR-T cell therapy, and now the disease has not recurred, creating a miracle in treating cancer. The therapeutic effect of cell therapy is constantly affirmed by doctors and patients, which brings new hope for the treatment of patients with advanced cancer. However, due to the particularity of cell therapy drugs, CMC and cost are still huge. How to apply the concepts of QbD and Risk Assessment to process development and production is the core of one-stop scheme. Tofflon can provide flexible solutions for cell therapy drugs from laboratory to large-scale production, with reliable whole station and honeycomb system providing flexible use scenarios and a complete consumable system, which can provide key support from research and development to the implementation of production strategies.

Tofflon Science and Technology Group Co., Ltd.

Purification Process
Cryopreservation Of The Original Solution
Auxiliary System
Preparation
Isolation System
Isolation System1
Isolation System2

Centrifugal

Membrane Filtration

Chromatographic Process

Parts

(M+E+C)&&AI&&

Relying on the understanding of regulations and processes, provide reliable end-to-end equipment and facilities from R&D to commercialization; Through planning and design, procurement management, engineering construction, system verification and other processes, integrated delivery of factories with specific functions; Provide core process consumables such as culture medium, filler, filter and disposable reaction bag to assist process optimization and solve the problem of stock solution production; Relying on the practical experience of informationization and intelligence, we will provide forward-looking and professional digital planning to help enterprises transform digitally.